Neuregulin 2 anticorps (Middle Region)

N° du produit ABIN3031975

Cet anticorps Lapin Polyclonal détecte spécifiquement Neuregulin 2 dans WB. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour Neuregulin 2 anticorps (Middle Region) (ABIN3031975)

Antigène: Neuregulin 2 (NRG2)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neuregulin 2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Neuregulin 2 anticorps

Épitope: Middle Region

Purification: Antigen affinity

Immunogène: An amino acid sequence from the middle region of human NRG2 (NGRKNSRLQFNKVKVEDA) was used as the immunogen for this NRG2 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the NRG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the NRG2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Neuregulin 2

Antigène: Neuregulin 2 (NRG2)

Autre désignation: NRG2

Sujet: Neuregulin 2, also known as DON1 or NTAK, is a protein that in humans is encoded by the NRG2 gene. Neuregulin 2 is a member of the neuregulin family of growth and differentiation factors. Through interaction with the ErbB family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The human gene contains 12 exons and the mouse Nrg2 gene contains 12 exons and spans about 180 kb. The genomic structure is similar to that of neuregulin 1(NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. In particular, the neuregulin-ERBB signaling pathways play crucial roles in regulating the proliferation and differentiation of Schwann cells, the myelin-forming cells in the peripheral nervous system.

UniProt: O14511

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway